Transforming a Former Postal Facility into a World-Class cGMP Development and Manufacturing Facility

by Jeff Kent POST at 200 Smith Street in Waltham, Mass. is a former U.S. post office repositioned into a 430,000sf office and lab building on a 36-acre campus. DPS Group and TRIA designed a new development and cGMP manufacturing facility for ElevateBio, a technology-driven company focused on powering cell and gene therapies for the…

Optimizing Space Requirements for Cell Therapy Manufacturing

Designs Deliver Millions in Cost Savings By Ankur Shah According to the Massachusetts Biotechnology Council (MassBio) 2022 Industry Snapshot, venture capital funding of the biopharma industry remained strong in 2022 with the first six months of the year boasting $5 billion invested in Massachusetts-headquartered biopharma companies. The strength of the Massachusetts early-stage ecosystem has translated…

cGMP facility conversions reflect demand for cleanrooms

The novel therapies start-up market has developed a need for small to midscale pre-clinical, clinical, and cGMP manufacturing cleanroom space. Many of these life-saving therapeutics are against the clock to build manufacturing space and search for alternatives that will save on speed to market. This market has also seen an influx of capital investment. According…

Design Considerations for Live Biotherapeutic Product Facilities Working with Spore-Forming Bacteria

Author: Judy Bodette, Principal Process Engineer, DPS Group; Aaron B. Cowley, Chief Science Officer, Arranta Bio; and Brian Duffy, Senior Director of Architecture and Engineering, DPS Group ­­Abstract: In this article, we will discuss the engineering concepts and considerations for a live biotherapeutic products (LBPs) manufacturing facility, along with the challenges associated with a novel…

cGMP facility conversions of existing real estate

In dense metropolitan areas like Greater Boston, undeveloped, appropriately zoned land for life sciences facilities with essential services and amenities nearby is becoming uncommon. Converting existing spaces to current good manufacturing practices or cGMP facilities rather than “greenfield” construction is trending, with drivers including speed to market, cost, and location.   DPS Group works with…

DPS Group and Hodess Cleanroom Construction Complete Proprietary Cell Therapy Manufacturing Facility for Mustang Bio

DPS Group, a privately-owned, global engineering company, and Hodess Cleanroom Construction, a comprehensive cleanroom construction company, today announced that they have completed a proprietary cell therapy manufacturing facility for Mustang Bio, Inc., a clinical-stage biopharmaceutical company. Mustang Bio engaged Hodess as prime consultant on the design/build project, and Hodess selected DPS Group for its depth…

Facility Profile: Mustang Bio Cell Therapy Manufacturing Facility

  by MaryBeth DiDonna, Editor Size: 27,000 sf Project team: DPS Group (engineering, architectural services), Hodess Cleanroom Construction (construction, prime consultant) Description: Mustang Bio’s new CAR T and gene therapy development facility is located within UMass Medicine Science Park in Worcester. It will support the clinical development and commercialization of Mustang’s CAR T and gene…

DPS Group & TRIA Complete Moderna Facility

The 200,000 sq. ft. space consolidates elements of Moderna’s development, operations and nearly 200 employees under one roof DPS Group and design affiliate TRIA have completed a new 200,000 square foot cGMP mRNA clinical manufacturing facility for Moderna Therapeutics. DPS and TRIA provided full architectural, engineering design, and project management services for the new clinical development manufacturing facility located…

Moderna Completes Norwood Biotech Manufacturing Facility

Moderna Therapeutics has completed its new 200,000-square-foot biotech manufacturing facility on Upland Road in Norwood following a fast-tracked two-year construction schedule. With nearly 200 employees, the 2-story facility located on a 28-acre parcel consolidates Moderna’s operations previously located in three properties in Cambridge. The Norwood facility will be used to develop materials for preclinical studies and…