The Science of Mitigating Supply-Chain Challenges

by Alvaro Ribeiro The impact of a global pandemic on the complex, interconnected nature of supply chains has quite literally brought home to us how fragile that infrastructure is in today’s global economy. While there are signs of recovery, it is impossible to predict the availability of commonplace products, let alone highly specialized building materials…

Office Environment Paradigms Shift to Surmount the Pandemic

By Janet Morra, AIA, LEED AP, Principal and Partner at Margulies Perruzzi     Evolution: Then and Now Since COVID-19 first appeared in early 2020 and triggered a pandemic, those on the front lines of building ownership, facilities management, design, and construction quickly took the lead in adapting office environments to evolving criteria for protecting…

cGMP facility conversions reflect demand for cleanrooms

The novel therapies start-up market has developed a need for small to midscale pre-clinical, clinical, and cGMP manufacturing cleanroom space. Many of these life-saving therapeutics are against the clock to build manufacturing space and search for alternatives that will save on speed to market. This market has also seen an influx of capital investment. According…

Design Considerations for Live Biotherapeutic Product Facilities Working with Spore-Forming Bacteria

Author: Judy Bodette, Principal Process Engineer, DPS Group; Aaron B. Cowley, Chief Science Officer, Arranta Bio; and Brian Duffy, Senior Director of Architecture and Engineering, DPS Group ­­Abstract: In this article, we will discuss the engineering concepts and considerations for a live biotherapeutic products (LBPs) manufacturing facility, along with the challenges associated with a novel…

cGMP facility conversions of existing real estate

In dense metropolitan areas like Greater Boston, undeveloped, appropriately zoned land for life sciences facilities with essential services and amenities nearby is becoming uncommon. Converting existing spaces to current good manufacturing practices or cGMP facilities rather than “greenfield” construction is trending, with drivers including speed to market, cost, and location.   DPS Group works with…

The Future of Telehealth Beyond COVID-19

by John Fowler, AIA, EDAC, LEED AP, Associate Principal and Associate Partner at Margulies Perruzzi The Margulies Perruzzi Healthcare Studio is seeing the impacts of COVID-19 on space planning and design that will continue post- pandemic in several areas. In addition to considerations for being better prepared for a future pandemic, clients are evaluating the…

Can Tech Soothe COVID Concerns in the Office?

Developers, Architects Assess Workplace Strategies   Office building owners better brace themselves for possible multimillion-dollar facility upgradesif they’re going to successfully lure back health-conscious tenants after the pandemic crisis finally eases.  Despite a rocky start to the state and nation’s vaccine rollout, there’s growing confidence that the end is insight for the now year-old COVID-19…